Biomimetic synthetic biology

Living filtration
for polluted
estuaries.

A biomimetic synthetic-biology platform inspired by oyster reefs, designed to capture microplastics, bind heavy metals, recover nutrients and regenerate urban waterways.

  • 4Pollutant classes sorted
  • 7Contained module types
  • 0Engineered cells released
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01 — The problem

Estuaries are overloaded with pollutants that biology already knows how to sort.

Urban waterways carry a tangled load: nitrogen and phosphorus runoff, dissolved heavy metals, microplastic fibres and fragments, and bacterial contamination. Conventional treatment can capture much of this, yet it rarely separates the streams or turns them into anything useful.

Oyster reefs solve a version of this every day. They couple particle filtration, biodeposition and microbial nutrient cycling into one living surface. M.OYSTER takes that biological logic and rebuilds it as contained engineered infrastructure.

i

Microplastics

Fibres, fragments and beads that pass through coarse screens and accumulate through the food web.

ii

Heavy metals

Dissolved Pb, Cd, Cu, Hg, Zn and Cr that persist and concentrate in sediment and tissue.

iii

Nitrogen + phosphorus

Excess nutrients that drive algal blooms, hypoxia and the collapse of estuarine oxygen.

iv

Pathogens + biofilms

Bacterial loads and opportunistic biofilms that degrade water quality and habitat.

02 — Model organism

Model organism:
the oyster reef.

A single oyster filters tens of litres of water a day. A reef turns that individual behaviour into a self-building ecosystem. Each step in its process maps onto an engineering function we can contain and control.

  1. 1

    Water enters

    Tidal flow draws turbid water across the reef surface.

  2. 2

    Gills + mucus capture

    Cilia and mucus trap suspended particles and bacteria.

  3. 3

    Labial palps sort

    Material is graded by size and quality before ingestion.

  4. 4

    Pseudofeces form

    Rejected particles are bound and deposited, not dispersed.

  5. 5

    Microbes transform

    Sediment communities cycle nitrogen and phosphorus.

  6. 6

    Reef builds habitat

    Shell accretion creates structure for new life.

03 — System architecture

A synthetic gill–mucus–sediment interface.

Seven contained modules, arranged in sequence. Water moves through capture, concentration and recovery stages. Every engineered cell stays behind a retaining membrane, and every pollutant exits as a separated, removable stream.

A

Synthetic gill layer

Electrospun nanofibre membrane and cilia-like flow structures capture particles, bacteria and microplastics.

B

Living mucus layer

Chitosan–alginate or bacterial-cellulose hydrogel hosts an engineered biofilm matrix for particle binding and pollutant concentration.

C

Heavy-metal capture cassette

Contained engineered biofilm senses metals and upregulates extracellular binders: metallothionein-like, phytochelatin-like and histidine-rich proteins.

D

Microplastics capture cassette

Synthetic gill fibres and living hydrogel aggregate microplastics into removable flocs.

E

Struvite recovery module

Ammonium and phosphate are recovered as magnesium ammonium phosphate crystals.

F

Sediment-mimic biofilm zone

Contained microbial communities support nitrification and denitrification.

G

Solid-deposit chamber

Pollutants are routed into separated, removable streams rather than released back into the water column.

Design graph — TuringDB

Trace every claim from pollutant to paper.

The whole design is held as one connected graph in TuringDB: pollutants, mechanisms, materials, engineered parts, cassettes, outputs, streams, risks, sensors and the literature behind each claim. Pick a pollutant and follow it from intake to recovered value, with a live check on whether it can reach the fertiliser.

58 nodes 92 edges 15 node types 16 relationship types

Capture

What captures it?

Every material, mechanism and cassette acting on a pollutant, and which engineered parts bind it on which chassis.

Safety

Can it reach the fertiliser?

Every contamination path into the struvite product stream, with the separation rules that must hold.

Value

Where does it end up?

The full route from module to output to stream to valorisation endpoint.

Evidence

What backs the claim?

The papers behind each mechanism and part, the failure modes per module, and the sensor watching each one.

Explore the design graph

04 — Module deep-dives

Three capture chemistries, three separate streams.

Heavy metals

Living metal-sequestering mucosa.

A contained engineered living material detects Pb, Cd, Cu, Hg, Zn and Cr, produces an extracellular binding matrix, and concentrates metals into harvestable biomass. The metal stream stays isolated from nutrient recovery at every stage.

Microplastics

Plastic-rich pseudofeces.

Electrospun gill fibres and mucus-like hydrogels capture plastic fibres, fragments and beads. An engineered extracellular matrix aggregates fine microplastics into removable flocs ready for downstream upcycling.

Nutrients

Pollution into mineral product.

A pH-buffered, magnesium-rich chamber recovers ammonium and phosphate as struvite, producing a solid nutrient product while keeping metals and microplastics out of the fertiliser stream.

05 — Valorisation

From pollutant to material stream.

Nutrient

Struvite

Recovered crystals as a slow-release fertiliser candidate.

Base metals

Cu, Ni, Zn

Routed toward electrodeposition or selective precipitation.

Toxic metals

Pb, Cd, Hg

Stabilised for specialist recovery and safe handling.

Carbon

Microplastics

Porous carbon, hard-carbon battery anodes, graphene-like nanomaterials, membranes or fuel and chemical feedstocks.

Biomass

Organic biomass

Treated separately according to contamination level.

Valorisation only happens after stream separation and contaminant testing.

06 — Safety + containment

Designed for containment, not release.

This is not an open-release system. Engineered cells are held inside replaceable cartridges behind retaining membranes, and the architecture is built to be serviced, monitored and regenerated offline.

  • Physical cell-retaining membranes
  • Replaceable sealed cartridges
  • Separate pollutant streams
  • Downstream guard layers
  • No environmental release of engineered cells
  • Sensor readouts for saturation, pH, flow resistance and breakthrough
  • Offline regeneration and servicing
07 — Research roadmap

Roadmap from benchtop to estuary.

  1. Phase 1

    Abiotic gill + mucus prototype

    Electrospun membranes and hydrogel layers characterised without living cells.

  2. Phase 2

    Contained living hydrogel cassette

    Engineered biofilm integrated and retained behind membranes.

  3. Phase 3

    Capture validation

    Heavy-metal and microplastic capture quantified under flow.

  4. Phase 4

    Recovery + separation

    Struvite recovery and stream separation demonstrated together.

  5. Phase 5

    Dockside contained pilot

    A sealed module tested in real estuarine conditions.

  6. Phase 6

    Modular reef-scale deployment

    Arrays of cartridges assembled into reef-scale infrastructure.

08 — The question

Can engineered living materials become ecological infrastructure?

We are building a new class of bio-designed filtration systems that learn from reefs, mucosa and sediment microbiomes.

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